Hedrick Lab at LJI | Life Without Cancer | Life Without Heart Disease
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There are 3 main areas of research in the lab. A primary goal in the laboratory is to study and target monocytes to aid in the prevention of cancer. Some monocytes are pro-tumoral, and other monocyte subsets are anti-tumoral, as we have shown that nonclassical monocytes prevent tumor metastasis. We want to understand more about how these monocyte subsets impact cancer initiation and progression. The second research goal is to study neutrophil heterogeneity in cancer and cardiovascular disease. We use high dimensional methods including CyTOF mass cytometry and single cell RNA-Sequencing to identify new myeloid cell subsets that may be important in disease. A third aim in the lab is to study how T cells are modulated by high cholesterol (such as LDL) to contribute to cardiovascular disease.
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